Friday, June 14, 2013

biochemistry is taking its upper hand. =)

salamzzz (sollu 'ala nabi)

zzzz...

happy studying saya ucapkan kepada rakan2 yang sedang menjalani ibadah belajar, didoakan moga kita semua berada di bawah jagaan Allah selalu.

petang2 camni dok hapdet belog sambil makan anggur hijau fresh rubuk kilo,ahh nyaman sekali terasa,sambil pipi ditampar halus oleh angin bayu berpuput indah (ayat sastera habih,,kuikui)

daripada duk saja,harini saya nak kongsi lah sedikit mnemonics ataupon akronim untuk pelajar medik di luar sana

hurm diingatkan mnemonics ni bukanlah saya yg buat..all credits goes to mr mohamed el sayed budak arab medical student satu uni dengan saya.lulz, (bajet jeh dia baca post ni)

akronim ni applicable utk subjek biochem je hokey! jangan nak apply kat subjek anatomy pulak, ahakz ok itu tak lawak yana.

tadi masa saya tengah dok bukak home facebook,keluar lah post dari page BEYOND EXCEPTIONAL MD'S (mohon like page tersebut ye,i'm one of the admins lulz-bajet-gila-hang) pasal mnemonics ni,saya yang tertarik dgn post itu lantas tanpa buang masa barang sesaat dua terus meng kopi dan pes tomato kannya ke dalam notes saya di desktop,pastuh dripada dok buang karen main fesbuk maka terhasillah satu idea bernas lagi takaful untuk menghapdet kannya di belog dan berkongsi pengetahuan ini dengan rakan2 semua.

tu dia panjang history taking aku buat pasal mnemonics ni. kalau rasa menyampah mohon skip baca part atas tu atau lempang diri anda laju2 pasai buang masa selama 30 saat baca part history taking tu.ahahah


ok berbalik kepada perkongsian ilmiah kita tadi,di sini adalah beberapa fakta secara random nya saya kongsikan,terima kasih kepada admins page beyond yg bersusah payah mengupdate post ini,jazakallahu khairan jazak.Allah saja mampu balas, =)

[Biochemistry Exam]

credits to Mohamed El Sayed

Glycogen storage diseases:
Anderson's (IV) &Cori's (III)
“ABCD”
Anderson's=Branching enzyme deficiency
Cori's=Debranching enzyme deficiency

Mc Ardle's(V)&Her's(VI)
“MM vs. HH”
both are due to glycogen phosphorylase deficiency,But
Mc Ardle's=Muscle glycogen phosphorylase (MM)
Her's=Hepatic glycogen phosphorylase (HH)

***Niacin deficiency: signs and symptoms
“4 D”
Diarrhoea
Dermatitis
Dementia
Death (if untreated)

***Creatine amino acid precursors
“ GAMA”
Glycine
Active Methionine (SAM)
Arginine

*** Fat soluble vitamins are:
“AKED”
Vitamin A
Vitamin K
Vitamin E
Vitamin D

***Carbon monoxide (CO) blocks electron transport chain at the level of
Cytochrome Oxidase (CO).

***(PH)enylketonuria is caused by a deficiency of (P)henylalanine (H)ydroxylase.

***RotenOne is an inhibitor of complex (I)one.

***The (LIV)er can oxidise all A.As except:
L…Leucine
I…Isoleucine
V…Valine


[Biochemistry Exam]

give two true vitamins acting as lipotropic factor?
1-folate
2-vitamin B12 (cobalamin)

because both act as methyl donor which help fomation of lipotropic factors ; which are subs. essential for ptn and PL synthesis like choline.

the same answer applies when the question asks :
''explain why methionine/ methyl donor/vitamin B12 is a lipotropic factor''




yang ni pulak differences between thiolase,thiokinase and thioesterase


THIOLASE
1.pathway: ketolysis
2.site: mitochondria
3.coenzyme: Co ASH

THIOKINASE
1. convert fatty acid to acyl CoA
2. cytosol
3. ATP, Co ASH

THIOESTERASE
1. de novo synthesis
2. cytosol
3. H2O

[Biochemistry Exam]

How aspirin acts in controliing myocardiac infarction?

Aspirin will inhibit COX enxyme, thus reduces the production of thromboxane and prostacyclin. However, the endothelium cells will produce new COX in matter of hours and lead to formation of prostacyclin. Whereas platelet can't manufacture the enzyme COX and the level of thromboxane rises only as new platelet enter the circulation. Small amount of aspirin for long period can decrease clot formation.

#action of prostacyclin: VD & inhibit paltelet aggregation
action of thromboxane: VC and promote platelet aggregation



[Biochemistry Exam]

Importance of Gluthathione: easy as ABCD :)

(A)mino acid transport/ absorption 
(B=P)owerful antioxidant
(C)ofactor in many enzyme - role GSH
(D)etoxification of aromatic a.a



maka sekian sahajalah persembahan akronim biochem dari saya,semoga perkongsian kali ni bermanfaat hendaknya

majulah biochem untuk medik!

ya Allah semoga nur liyana ab aziz mendapat mumtaz untuk subjek biochem pada tahun ini ya Allah,amin

syukran doakan saya!



wehooo~


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